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antibiotic resistance

London's water contains high levels of antibiotic-resistant genes, UCL research reveals

Research from University College London has warned that freshwater sources in the English capital of London contain high levels of antibiotic-resistant genes.

These genes, excreted in human and animal waste after antibiotic use, can provide bacteria with resistance to common antibiotics including penicillin, erythromycin and tetracycline.

The global rise in antibiotic resistance threatens infection prevention and cure

Published on 20/05/19 at 01:23pm

Dr Bill Love, Founder and Chief Scientific Officer of Destiny Pharma, discusses the rise of antimicrobial resistance (AMR), the antibiotic stewardship required to offset this global threat, and the additional incentivisation initiatives needed to promote innovation, as well as the role of preventative antimicrobial treatments as an important element of this global fight against AMR.

Top Ten most popular articles on Pharmafile.com this week!

News that the FDA’s advisory panel had recommended Janssen’s intranasal esketamine spray Spravato as a treatment for treatment resistant depression, took the top spot this week. The therapy, based on party drug ketamine, may act as a significant breakthrough in the neglected area of mental health.

Other news saw England’s chief medical officer Dame Sally Davies, who is leaving her current role to become Master of trinity College Cambridge, suggest that as many as one third of antibiotics may be prescribed inappropriately.

MSF warns of antibiotic resistance crisis in Gaza

Image Credit: Boris Niehaus

The international non-governmental organisation (NGO) Médecins Sans Frontières (MSF) has warned that antibiotic resistant infections are a “certainty” in Gaza.

The medical NGO has declared that “action must be taken,” to prevent an epidemic of antibiotic resistance in the Israeli occupied Palestinian territory.

The NGO has suggested that the crisis has been compounded in recent months by “the violent response of Israeli forces to Palestinian protestors in Gaza”.

Antibiotic combinations could help in fight against antimicrobial resistance

Image Credit: b r e n t https://www.flickr.com/photos/bmh4you/371628984

Antimicrobial resistance (AMR) could be tackled by giving people a combination of antibiotic drugs that are no longer effective on their own, a new study from researchers at the University of California suggests.

The University of California researchers discovered approximately 8000 different combinations of antibiotic drugs, that when combined are effective in fighting bacteria even if those bacteria are able to resist each specific drug individually. The scientists outlined their findings in the journal Systems Biology and Applications.

Wockhardt launches $40m manufacturing plant in Dubai

Indian pharmaceutical firm Wockhardt has launched its first manufacturing facility in Dubai’s Jebel Ali Free Zone (Jafza). Costing $40 million, the new site will focus on the manufacture of New Chemical Entities (NCEs) to global markets; in particular, it will produce antibiotics designed to combat “superbugs” in the fight against antimicrobial resistance.

At the launch event, Murtaza Khorakiwala, Managing Director of Wockhardt, remarked: “This antibiotic works on organisms that have built resistance to antibiotics, so in a way, this will satisfy an unmet medical need.”

The mission against antimicrobial resistance

Published on 23/07/18 at 11:39am
Image Credit: Dr Graham Beards at en.wikipedia

Two headlines have highlighted the ‘here and now’ of the threat of rising antimicrobial resistance (AMR), writes Dr Peter Jackson.

A study reported in The Lancet Infectious Diseases found that antibiotics are now failing to work in a fifth of patients who suffer an infection after hospital surgery.

This global research, looking at 13,000 patients across 66 countries, found that over 12% of those undergoing procedures developed a post-operative surgical site infection (SSI). 

University of Adelaide is fighting antibiotic-resistant superbugs by starving them of iron

Image credit: Russell Millard/University of Adelaide

A team of researchers from Australia’s University of Adelaide have developed a new method to fighting antibiotic-resistant bacteria by starving it of iron, the fuel it needs grow and threaten human health.

FDA launches new method for antibiotic prescription

The fight against the growth of antibiotic resistance has become a major talking point internationally in recent years and the FDA has announced its own method to aid the effort.

Antibiotic development is inadequate to meet global resistance threat, WHO warns

The World Health Organization (WHO) has released a report indicating that worldwide development of new antibiotics is not keeping pace with the rising prevalence of antimicrobial resistance, with the risk that we may face an inability to meet growing demand.

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