Image Credit: Jimjamjak
A 20 year old man died after a single leukaemia cell accidentally ended up in a batch of cells that were being manufactured into a CAR-T cell therapy, according to researchers at the University of Pennsylvania.
The mistake, which brought about a fatal relapse in the 20 year old man, was reported in the journal Nature Medicine.
The patient was entered into an early stage trial of CTL019, which was eventually licensed to Novartis and sold under the brand name Kymriah.