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FDA rejects Insys Therapeutics sublingual opioid spray

US regulators FDA building

The FDA has rejected Insys Therapeutics buprenorphine sublingual spray due to concerns about the safety of the Arizona-based company’s opioid painkiller.

The US regulator’s decision has come after the FDA advisory committee voted 18-1 against approval of the treatment. The American company sought approval for the sublingual spray, which uses the active ingredient buprenorphine, for the treatment of moderate to severe acute pain earlier this year. However the FDA has rejected the application due to potential safety concerns.

Illegally manufactured fentanyl drives deaths in Ontario

Toronto, Ontario skyline

Illicit forms of the powerful opioid fentanyl have been driving increased rates of opioid-related deaths in the Canadian province of Ontario.

Of the 1,263 opioid related deaths that occurred in Ontario last year, 68% involved fentanyl compared to 45% in 2016. Illegally produced, non-pharmaceutical fentanyl was responsible for 78% of deaths related to the powerful synthetic opioid, which can be up to 100 times more potent than morphine. 

Talking Point: Crisis Management

Published on 02/07/10 at 08:00am
Kirsty Mearns

Crisis (noun): a situation that has reached an extremely difficult or dangerous point; a time of great disagreement, uncertainty or suffering.

I don’t mind admitting that I am a ‘glass half empty’ type of person. When presented with an opportunity I can have a tendency to see the downside. While this trait of mine can be somewhat irritating for those people who are optimists in life, it can have its advantages.

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