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US Government awarded new patent on preventative HIV drugs PrEP

The Department of Health and Human Services (HHS) has been awarded a new patent on drugs that prevent HIV.

The US Patent office has awarded the US government a patent on drugs derived from HIV drug Tenofovir that inhibit the transmission of HIV.

The new patent may reignite a dispute between the government and PrEP drugmaker Gilead over the rights to PrEP drug Truvada and its successor Descovy.

In May 2019, campaigners called on the government to enforce the CDC’s patents on the use of Truvada as a preventative treatment for HIV.

Gilead signs deal with Nurix Therapeutics worth more than $2.3 billion

Gilead has signed a deal with San Francisco biotech Nurix Therapeutics – a company focused on developing drugs that control levels of the enzyme ubiquitin E3 ligases which are responsible for the breakdown of proteins in human cells.

Dysregulated and/or mutated proteins play a central role in the development and progression of many human diseases. It is hoped that by controlling protein levels Nurix’s technologies will be able to tackle cancer and other challenging diseases.

Gilead inks deal with Canadian antibody discovery firm AbCellera

Gilead has entered into an agreement with Canadian monoclonal antibody discovery firm AbCellera.

The two firms will take part in a cross border collaboration to support the discovery of new therapeutic antibody candidates for infectious diseases.

Under the terms of the agreement AbCellera will receive upfront and research payments and is eligible to receive downstream clinical and commercial milestone payments and royalties on net sales of products.

Long-term BMS exec Johanna Mercier joins Gilead as new Chief Commercial Officer

Published on: 07/06/19

Gilead Sciences have said Bristol-Myers Squibb exec Johanna Mercier will be the firm’s new Chief Commercial Officer.

In her new role Mercier will join Gilead’s senior leadership team when she takes over the California firm’s commercial operations on July 1.

Mercier, who served with BMS for more than ten years, brings a wealth of experience to the role. The experienced executive holds a degree in Biology from the University of Montreal and an MBA from Concordia University.

Long term BMS exec Johanna Mercier joins Gilead as new Chief Commercial Officer

Gilead Sciences have said Bristol-Myers Squibb exec Johanna Mercier will be the firm’s new Chief Commercial Officer.

In her new role Mercier will join Gilead’s senior leadership team when she takes over the California firm’s commercial operations on July 1.

Mercier, who served with BMS for more than ten years, brings a wealth of experience to the role. The experienced executive holds a degree in Biology from the University of Montreal and an MBA from Concordia University.

Top Ten most popular articles on Pharmafile.com this week

On the day that UK Prime Minister Theresa May announces her resignation, we look back on the week's biggest stories in the pharmaceutical industry.

Top Ten most popular articles on Pharmafile.com this week!

Some big names – including Gilead, Janssen, Teva and Bristol-Myers Squibb – were in trouble this week after two separate lawsuits accused them and others of suppressing competition. While Gilead had sought to retain dominance in the HIV drugs market, Teva was alleged to be at the centre of a conspiracy through which generic drugmakers divided up the market for generic meds.

Gilead CEO Daniel O'Day challenged over patents on PrEP drug Truvada

Image Credit: nrkbeta

On 16 May, Gilead CEO Daniel O’Day was grilled over the $1,780 price tag on PrEP drug Truvada in a US congressional hearing. At a cost of more than $21,000 a year, the preventative-HIV drug is 222 times more expensive in the US than it is in Australia, where it costs just $8.

Explaining the price discrepancy, O’Day said: “Truvada still has patent protection in the United States, and in the rest of the world it is generic. It will be generically available in the United States as of September 2020.”

Gilead struck anti-competitive deals to retain dominance in HIV market, lawsuit says

Gilead Sciences struck anti-competitive deals with Janssen and Britsol-Myers Squibb in an effort to retain dominance in the market for HIV drugs, according to a lawsuit filed by AIDS activists and unions.

The California firm colluded with BMS and J&J – whose medicines were used in a drug combination cocktail – to prevent generic competition, the lawsuit says.

The lawsuit alleges the two companies agreed to only use Gilead’s version of tenofovir, even after Gilead’s patent had expired.

Gilead will give 11 years’ worth of PrEP drugs to those at risk of HIV after 'discussions' with Trump

Gilead Sciences has agreed to donate 11 years’ worth PrEP drugs for up to 200,000 individuals each year, following “discussions between the Trump Administration” and the California firm.

Gilead Sciences will give preventative HIV drug Truvada to uninsured individuals who are at risk of being infected with HIV, Health and Human Services Secretary Alex Azar said.

The agreement will last until at least the end of 2025 and may continue through to December 31 2030.

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