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Top Ten most popular articles on Pharmafile.com this week

The first day of June - time for another top ten run-down. It's been a week somewhat characterised by trial failures, terminations, and job cuts, but there have been triumphs too. Perhaps one of the most striking stories this week was the news that a Google AI platform showed the capacity to identify skin cancer with greater accuracy than more than 50 professional dermatologists after it was trained to do so.

Insider Interview: Gilead's fight against HIV comes into bloom

Published on 30/05/18 at 11:12am

Mike Elliott, Vice President of Medical Affairs at Gilead (pictured, right), chats about the company’s sponsorship of a 'A life without walls' at the annual Chelsea Flower Show in London last week a garden dedicated to combating the stigma surrounding HIV as well as its rejuvenated efforts to cure the disease.

How did the project come to be?

Gilead expands operations in Cork, Ireland

Gilead has unveiled the expansion of its Cork manufacturing site, involved in the creation of its treatments for HIV and hepatitis.

The €9.5 million quality control lab facility has been opened to accommodate the biotech’s growing presence in Ireland, after it invested close to €200 million to build a manufacturing infrastructure that now employs more than 500 people. It’s a rapid scale-up, considering Gilead established a presence in Ireland less than two decades ago.

Novartis becomes first to gain second CAR T indication

Novartis has announced that its CAR T treatment, Kymriah, has successfully been given a second indication for the treatment of relapsed or refractory large B-cell lymphoma after two or more lines of treatment.

The approval brings Kymriah into the same market space occupied by Gilead’s rival treatment, Yescarta. Most importantly for Novartis, It opens up a new patient pool and will see sales of the drug increase, after a sluggish start to life on the market.

US court upholds verdict voiding MSD's claim to $200m from Gilead in patent dispute

MSD has taken a legal hit after a US appeals court upheld a ruling that the pharma giant had illicitly obtained patent rights for the treatment of hepatitis C, voiding its claim to an infringement verdict against Gilead to the tune of $200 million.

New hepatitis C combo boasts 97% cure rate for just $300

Image Credit: BruceBlaus

A partnership of the not-for-profit organisation Drugs for Neglected Diseases initiative (DNDi) and Egyptian drug firm Pharco Pharmaceuticals is working to bring a new, effective and affordable combination therapy to patients with hepatitis C (HCV).

New Chief Science and Medical Officers for Gilead

Published on: 19/03/18

Gilead has announced that Dr Norbert Bischofberger, its Chief Scientific Officer (CSO), Executive Vice President of Research and Development and a veteran of almost 30 years at the company, will be leaving his position at the end of April. He will be succeeded by Dr John McHutchison (pictured), who will step up from his current role as Executive Vice President of Clinical Research to assume the mantle of CSO as well as responsibility for Gilead’s R&D organisation.

Top Ten most popular articles on Pharmafile.com this week

After a particularly jarring bout of cold weather and snow, we may just have seen off the worst of winter here in the UK. So there's the hope that Spring is just around the corner as we pass another Friday and another top ten rundown of the week's most popular articles.

Switching to Gilead's Biktarvy proves non-inferior in HIV patients

Gilead has unveiled findings from two Phase 3 studies into the efficacy of switching to its three-drug combo Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) from a range of regimens.

Gilead investigational data gives hope for HIV eradication in humans

Gilead has lifted the curtain on new preclinical data on the efficacy of a combo therapy of GS-9620, its investigational oral toll-like receptor 7 (TLR7) agonist, and the broadly neutralising antibody (bNAb) PGT121, in the eradication of HIV in non-human primates.

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