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Novartis' CAR T therapy Kymriah to become available on the NHS

Novartis’ Kymriah is set to become the first CAR T therapy to become available on the NHS after it was revealed that the cancer treatment will be offered to children and young adults up to the age of 25 years old with B-cell acute lymphoblastic leukaemia (ALL) that is refractory, in relapse post-transplant or in second or later relapse.

While both Gilead and Novartis’ CAR T therapies were awarded marketing authorisation in the European Union just last week, NICE were quick to reject Gilead’s CAR T therapy Yescarta on the grounds that it was too expensive.

Novartis' Kymriah & Gilead's Yescarta become first EU-approved CAR T therapies

Almost one full year since the treatment was given a “historic” approval in the US, Novartis’ CAR T therapy Kymriah (tisagenlecleucel) has been awarded marketing authorisation in the EU for the treatment of blood cancer. Its rival, Gilead/Kite Therapeutics’ Yescarta (axicabtagene ciloleucel) has also been authorised, marking the first approval of its kind in the region.

As CAR-T therapies, both are manufactured from immune cells derived from a specific patient’s body.

Gilead CMO announces departure alongside two new exec appointments

Published on: 17/08/18

Gilead has announced that its Chief Medical Officer is to vacate the role after just five months and leave the company in order to “pursue another opportunity”.

Gilead CMO announces departure alongside two new exec appointments

Gilead has announced that its Chief Medical Officer is to vacate the role after just five months and leave the company in order to “pursue another opportunity”.

Dr Andrew Cheng will remain at Gilead until 7 September to aid in the transition period.

Gilead's CEO and Chairman to both step down before year's end

Published on: 30/07/18

Gilead has announced that its President and Chief Executive Officer Dr John Milligan (pictured) will be stepping down by the end of the year, ending his run of 28 years at the company. He will remain in the role while the Board of Directors searches for a successor.

Alongside him, it has also been revealed that Chairman Dr John Martin will also be leaving the company. He has said he will vacate his position on the Board when a replacement CEO has been found.

Top Ten most popular articles on Pharmafile.com this week

With the UK in the grip of a record-breaking heatwave, it's hard to focus on much else over here, but it's been another packed week in the pharma industry.

The Brexit farce continues as the UK Government has admitted that the NHS will need to stockpile medicines in the event no deal can be reached with the EU on an exit deal, and Roche and AstraZeneca have followed in Pfizer's footsteps with pledges to pause price hikes until 2019, after the latter firm was chastised over social media by President Donald Trump.

But the most-read story this week is the heart-breaking news th

Gilead's CEO and Chairman to both step down before year's end

Image Credit: Gilead

Gilead has announced that its President and Chief Executive Officer Dr John Milligan (pictured) will be stepping down by the end of the year, ending his run of 28 years at the company. He will remain in the role while the Board of Directors searches for a successor.

Alongside him, it has also been revealed that Chairman Dr John Martin will also be leaving the company. He has said he will vacate his position on the Board when a replacement CEO has been found.

Top Ten most popular articles on Pharmafile.com this week

The first day of June - time for another top ten run-down. It's been a week somewhat characterised by trial failures, terminations, and job cuts, but there have been triumphs too. Perhaps one of the most striking stories this week was the news that a Google AI platform showed the capacity to identify skin cancer with greater accuracy than more than 50 professional dermatologists after it was trained to do so.

Insider Interview: Gilead's fight against HIV comes into bloom

Published on 30/05/18 at 11:12am

Mike Elliott, Vice President of Medical Affairs at Gilead (pictured, right), chats about the company’s sponsorship of a 'A life without walls' at the annual Chelsea Flower Show in London last week a garden dedicated to combating the stigma surrounding HIV as well as its rejuvenated efforts to cure the disease.

How did the project come to be?

Gilead expands operations in Cork, Ireland

Gilead has unveiled the expansion of its Cork manufacturing site, involved in the creation of its treatments for HIV and hepatitis.

The €9.5 million quality control lab facility has been opened to accommodate the biotech’s growing presence in Ireland, after it invested close to €200 million to build a manufacturing infrastructure that now employs more than 500 people. It’s a rapid scale-up, considering Gilead established a presence in Ireland less than two decades ago.

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