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Patients to recieve MDMA-assisted psychotherapy on 'compassionate' grounds in Israel

The Israeli Health Ministry has approved the compassionate use of MDMA-assisted psychotherapy for 50 patients with post-traumatic stress disorder (PTSD).

The Israeli government currently classify MDMA as a ‘dangerous drug’ While recreational use of MDMA is illegal, the government allow use of MDMA in clinical trials.

However compassionate use allows drugs that are still in development to be made available to patients outside of a clinical trial due to lack of effective alternatives.

76% of patients no longer experience PTSD a year after MDMA-assisted psychotherapy

Promising phase II results suggest that MDMA-assisted psychotherapy may be an “innovative, efficacious treatment for posttraumatic stress disorder,” according to a study published in the Journal of Psychopharmacology.

Strikingly, the double-blind, placebo-controlled phase II trial, which supports the case for MDMA as a treatment for PTSD, found that 76% of patients no longer had PTSD 12 months after undertaking their third active-dose MDMA assisted psychotherapy session.

Tonix plunges 68% after PTSD drug failure

Tonix Pharmaceuticals has announced that it has terminated its Phase 3 study of Tonmya (cyclobenzaprine HCl sublingual tablets) in military-related posttraumatic stress disorder (PTSD) after the drug failed to prove adequate separation from placebo in its primary endpoint.

Recreational drug MDMA proves efficacy in reducing PTSD symptoms, new study finds

Promising new findings have been revealed in the efficacy of MDMA in treating post-traumatic stress disorder (PTSD).

FDA fast-tracks recreational drug MDMA for treatment of PTSD

In another leap forward for the promising treatment, the FDA has announced that it has granted Breakthrough Therapy Designation to MDMA for the treatment of post-traumatic stress disorder (PTSD).

The US regulator has also come to an agreement with the Multidisciplinary Association for Psychedelic Studies (MAPS) on the design of two upcoming Phase 3 trials to test the drug through MDMA-assisted psychotherapy in severe forms of the condition, the first of which will begin enrolment in Spring 2018.

Common antibiotic shows promise as novel PTSD treatment

Research coming out of University College London (UCL) and the University of Zurich has indicated that common antibiotic doxycycline could be used to prevent or treat post-traumatic stress disorder (PTSD) as evidence emerges of its ability to disrupt negative associations in the brain.

MDMA trials get FDA backing for PTSD treatment

The FDA have given the go-ahead to Phase 3 clinical trials investigating the efficacy of MDMA (Methylenedioxymethamphetamine) for treating post-traumatic stress disorder (PTSD), a promising step on the road for the traditionally recreational drug to become a prescribed therapy.

Tonix tanks after Phase III failure

New York-based Tonix Pharmaceuticals has suffered an almost 60% fall in their share price, after the announcement that its fibromyalgia drug candidate, TNX-102 SL, failed to significantly reduce pain in a Phase III trial.

Digital Pharma - Online patient recruitment drive for GSK’s anxiety drug

Published on 26/01/10 at 07:15am
COPE study website

GlaxoSmithKline is readying to move its post-traumatics stress disorder candidate orvepitant into phase II trials, a move being supported by an online patient recruitment drive.

The 12-week COPE (Clinical Trial with Orvepitant in PTSD Experiencers) trial aims to enroll around 240 patients across 25 sites in the US.

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