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Janssen privy to new pricing scheme and see NICE nod

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Janssen’s hepatitis C drug Olysio has been approved by NICE whilst also reaching a novel ‘pay if you clear’ pricing agreement with the NHS.

The payment scheme means that NHS England will only pay for Olysio (simeprevir) if patients are effectively cured of the virus after 12 weeks of treatment, with Janssen refunding the cost for those who aren’t. Trials so far have found a cure rate of around 80% after 12 weeks of using the drug.

FDA approves Olysio

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US regulators have approved Janssen Pharmaceuticals’ Olysio, a new therapy to treat chronic hepatitis C virus infection, after a priority review.

Protease inhibitor Olysio (simeprevir) blocks a specific protein needed by the hepatitis C virus to replicate and is approved for use in combination with peginterferon-alfa and ribavirin.

It will be used in treatment-naïve adults with compensated liver disease - that is, a diseased liver that is still functioning - which may include cirrhosis, or patients for whom previous treatment has not been effective.

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