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triple-negative breast cancer

Keytruda fails to improve overall survival in advanced triple-negative breast cancer

MSD has made it known that its cancer immunotherapy Keytruda (pembrolizumab) failed to meet its primary endpoint in a Phase 3 study evaluating its efficacy as a monotherapy for the second- or third-line treatment of metastatic triple-negative breast cancer (TNBC).

The company revealed that the blockbuster anti-PD-1 drug failed to show superiority in improving overall survival compared to chemotherapy (capecitabine, eribulin, gemcitabine or vinorelbine). Because this primary endpoint was never met, all other endpoints were not formally tested.

University of Virginia researchers identify new target in triple-negative breast cancer

Researchers at the University of Virginia claim they have discovered a new target for triple-negative breast cancer, a notoriously aggressive and difficult-to-treat form of the disease.

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