Skip to NavigationSkip to content

NICE gives thumbs-up to Roche's Kadcyla in HER2+ breast cancer sub-population

Published on 07/05/20 at 01:00pm

NICE has revealed that it has recommended the NHS use of Roche’s Kadcyla (trastuzumab emtansine) for HER2+ breast cancer in patients who have residual invasive disease in the breast or lymph nodes after receiving neoadjuvant treatment including a HER2-targeted agent.

HER2, or human epidermal growth factor receptor 2, is a cancer cell protein which is associated with larger tumours, higher risk of recurrence and poorer clinical outcomes in breast cancer. Around 7,000 breast cancer patients are diagnosed as HER2+ each year. It is estimated that around 800 patients in England and Wales will now be eligible to receive the drug through routine NHS use.

NICE moved to recommend the drug on the basis of clinical data demonstrating that Kadcyla improved progression-free survival compared to trastuzumab alone in patients who saw their tumours shrunk but not eliminated after receiving neoadjuvant therapy with a taxane chemotherapy and HER2-targeted treatment – a population who are at risk of disease re-emergence. However, final results on the therapy’s efficacy in extending overall survival have not yet been reached.

“Additional treatment options that can increase the amount of time in which people remain free of disease after surgery, and perhaps stop it from coming back altogether, are particularly welcome,” remarked Meindert Boysen, Deputy Chief Executive and Director of the Centre for Health Technology Evaluation at NICE. “We are therefore pleased to be able to recommend that trastuzumab emtansine is made available routinely for people with HER2-positive early breast cancer after surgery.”

While the average cost of Kadcyla stands at $51,000 per treatment, the NHS has negotiated a confidential discount with Roche.

Lesley Hugo, Breast Cancer Franchise leader at Roche, also commented: “Today’s news means that patients with early breast cancer will continue to benefit from the latest advancements in cancer care, where receiving effective treatment early in the disease is crucial to prevent recurrence. We are proud to have worked with the breast cancer community to achieve this milestone, one which represents a step forward in the treatment of this disease.”

Matt Fellows


I found your this post while searching for some related information on blog search...Its a good post..keep posting and update the information best instagram bots

Thanks for sharing the post.. parents are worlds best person in each lives of individual..they need or must succeed to sustain needs of the family. non profit

It is a great website.. The Design looks very good.. Keep working like that!. Celebrity style blog

I recently found many useful information in your website especially this blog page. Among the lots of comments on your articles. Thanks for sharing. school website design

Your website is really cool and this is a great inspiring article. record

Love what you're doing here guys, keep it up!.. CBD Health Benefits

Hi! Thanks for the great information you havr provided! You have touched on crucuial points! pizza and beer near me

Great! It sounds good. Thanks for sharing.. steak houses el paso

What a fantabulous post this has been. Never seen this kind of useful post. I am grateful to you and expect more number of posts like these. Thank you very much. kerja dari rumah

Excellent information on your blog, thank you for taking the time to share with us. Amazing insight you have on this, it's nice to find a website that details so much information about different artists. best Locksmith Virginia Beach

thanks for the tips and information..i really appreciate it.. league of legends account protection

thanks for this usefull article, waiting for this article like this again. Intex pools

I have read your blog it is very helpful for me. I want to say thanks to you. I have bookmark your site for future updates. website design Washington dc

I read that Post and got it fine and informative. Local movers San Diego

Nice post! This is a very nice blog that I will definitively come back to more times this year! Thanks for informative post. Elias Landsmanas

Nice knowledge gaining article. This post is really the best on this valuable topic. Porfirio Sanchez

I’ve been searching for some decent stuff on the subject and haven't had any luck up until this point, You just got a new biggest fan!.. Jack Landsmanas

I really enjoyed reading this post, big fan. Keep up the good work andplease tell me when can you publish more articles or where can I read more on the subject? funny pictures

I felt very happy while reading this site. This was really very informative site for me. I really liked it. This was really a cordial post. Thanks a lot!. brendan bannister

I am happy to find this post Very useful for me, as it contains lot of information. I Always prefer to read The Quality and glad I found this thing in you post. Thanks rv rental san diego

Thank you so much for sharing this great blog.Very inspiring and helpful too.Hope you continue to share more of your ideas.I will definitely love to read. Waschmaschine

Positive site, where did u come up with the information on this posting?I have read a few of the articles on your website now, and I really like your style. Thanks a million and please keep up the effective work. WordPress Web Design Agency London

Is it okay to post part of this on my website basically post a hyperlink to this webpage? Power Wash

Nice post mate, keep up the great work, just shared this with my friendz food diary

I am continually amazed by the amount of information available on this subject. What you presented was well researched and well worded in order to get your stand on this across to all your readers. Merchant Accounts

I gotta favorite this website it seems very helpful . Ohrringe Gold

Dentists at TiborDental can treat tooth decay perfectly.

A magasfokú képzettség és a szakmai tapasztalat azoktól, akik a nemzetközi szállítmányozás fontos feladatát végzik.

Hello, I have browsed most of your posts. This post is probably where I got the most useful information for my research. Thanks for posting, maybe we can see more on this. Are you aware of any other websites on this subject. detectives privados madrid

Your blog provided us with valuable information to work with. Each & every tips of your post are awesome. Thanks a lot for sharing. Keep blogging, innovation

I can set up my new idea from this post. It gives in depth information. Thanks for this valuable information for all,.. Black rifle coffee

I am happy to find this post Very useful for me, as it contains lot of information. I Always prefer to read The Quality and glad I found this thing in you post. Thanks best face masks

I have been checking out a few of your stories and i can state pretty good stuff. I will definitely bookmark your blog gtm discount coupons

I am unable to read articles online very often, but I’m glad I did today. This is very well written and your points are well-expressed. Please, don’t ever stop writing. gravestone

Hello I am so delighted I located your blog, I really located you by mistake, while I was watching on google for something else, Anyways I am here now and could just like to say thank for a tremendous post and a all round entertaining website. Please do keep up the great work. Bowers & Wilkins

I’ve read some good stuff here. Definitely worth bookmarking for revisiting. I surprise how much effort you put to create such a great informative website. Concierge services

Hello There. I found your blog using msn. This is an extremely well written article. I will be sure to bookmark it and return to read more of your useful information. Thanks for the post. I’ll certainly comeback. coupons for pedigree dog food

I recently found many useful information in your website especially this blog page. Among the lots of comments on your articles. Thanks for sharing. marble kitchen worktops

Thanks for sharing us. mold removal san diego

I found your this post while searching for some related information on blog search...Its a good post..keep posting and update the information tilt and turn windows

That appears to be excellent however i am still not too sure that I like it. At any rate will look far more into it and decide personally! All-Natural CBD Salves

I love this blog!! The flash up the top is awesome!! bonus 100 member baru sportsbook

شركة سيركو سورية تقدم خدمات كهرباء صحية تعهدات انشاء مقاولات بناء كهرباء كاميرات مراقبة اجهزة انذار اعمار اكساء دهانات في دمشق سورية سوريا مقاولات تعهدات دمشق سيركو سورية شركة

Very useful info. Hope to see more posts soon!. FAMILY INVESTIGATION IN SPAIN

I recently came across your blog and have been reading along. I thought I would leave my first comment. I don’t know what to say except that I have enjoyed reading. Nice blog, I will keep visiting this blog very often. Canada PR process

Thanks for taking the time to discuss this, I feel strongly about it and love learning more on this topic. Coffee beans

Thank you very much for keep this information. fliesenverlegung düsseldorf

Excellent website you have here, so much cool information!.. Concepteur 3d bijouterie

FREE Express Shipping by DHL - We used DHL that delivers in 3-4 days in the US, Canada, Australia, Japan, and the countries located in Western Europe. The delivery time is around a week for Eastern Europe, South Korea, and other countries. custom patches

Nice post. I was checking constantly this blog and I am impressed! Extremely helpful information specially the last part I care for such info a lot. I was seeking this particular information for a very long time. Thank you and good luck. Business Strategies for Contractors

Mission Statement is a leading portal for the pharmaceutical industry, providing industry professionals with pharma news, pharma events, pharma service company listings and pharma jobs,
Site content is produced by our editorial team exclusively for and our industry newspaper Pharmafocus. Service company profiles and listings are taken from our pharmaceutical industry directory, Pharmafile, and presented in a unique Find and Compare format to ensure the most relevant matches