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Researchers develop AI algorithm to diagnose deep vein thrombosis

Published on 16/09/21 at 10:14am

Researchers from the University of Oxford, Imperial College, and the University of Sheffield have developed a machine learning algorithm with the aim of diagnosing deep vein thrombosis (DVT) more quickly and as effectively as traditional radiologist-interpreted diagnostic scans.

The team of researchers, in collaboration with the tech company ThinkSono, trained a machine learning AI algorithm, AutoDVT, to distinguish patients who had DVT from those without DVT.

The AI algorithm accurately diagnosed DVT when compared to the gold standard ultrasound scan, and the team worked out that using the algorithm could potentially save health services $150 per examination.

Dr Nicola Curry, a researcher at Oxford University’s Radcliffe Department of Medicine and clinician at Oxford University Hospitals NHS Foundation Trust, said: “Traditionally, DVT diagnoses need a specialist ultrasound scan performed by a trained radiographer, and we have found that the preliminary data using the AI algorithm coupled to a hand-held ultrasound machine shows promising results”.

This is the first study to show that machine learning AI algorithms can potentially diagnose DVT, and the researchers are due to start a test-accuracy blinded clinical study, comparing the accuracy of AutoDVT with standard care to determine the sensitivity of the for picking up DVT cases. The hope will be that AutoDVT will get the right diagnosis faster to the nearly 8 million people worldwide who potentially have a venous blood clot each year.

The research team hope that the combination of the AutoDVT tool, with the inclusion of the AI algorithm, will allow non-specialist healthcare professionals, like GPs and nurses, to quickly diagnose and treat DVT. It may additionally allow the collection of images by non-specialists which could be sent to an expert facilitating diagnosis of those unable to get to a specialist.

Christopher Deane from the Oxford Haemophilia and Thrombosis Centre, said: “The AI algorithm can not only be trained to analyse ultrasound images to discriminate the presence versus the absence of a blood clot – it can also direct the user using the ultrasound wand to the right locations along the femoral vein, so that even a non-specialist user can acquire the right images”.

DVT is a type of blood clot most commonly formed in the leg, causing swelling, pain and discomfort - if left untreated, it can lead to fatal blood clots in the lungs. 30-50% of people who develop a DVT can go on to have long-term symptoms and disability.

The results of the study have been published in the journal Digital Medicine.

Kat Jenkins

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